Mastercard and Jonas Brothers to debut music video in support of Stand Up To Cancer

Today, Mastercard builds on 15 years of support for Stand Up To Cancer ® (SU2C) by launching a new initiative in partnership with the global pop superstars, Jonas Brothers. Through the unifying power of music, Mastercard and the Jonas Brothers are honoring the inspiring ways people stand up to cancer every day. By using your Mastercard to help support cancer research and sharing how you stand up on social, Mastercard is inviting everyone to join the movement to make a difference.

Now through August 22nd, Mastercard will donate one cent, up to $5 million dollars, to Stand Up To Cancer when cardholders tap or order online with their Mastercard at qualifying restaurants and grocery stores - giving consumers an easy way to turn everyday purchases into something powerful*.  

To kick off the collaboration, Mastercard surprised Jonas Brothers superfans and their loved ones impacted by cancer with a once-in-a-lifetime experience. What began as an invitation to share their stories became a powerful moment of celebration and connection - culminating in an intimate moment with the Jonas Brothers and the debut performance of “I Can’t Lose,” the brands brand-new single dropping later today off their upcoming album Greetings from Your Hometown.  

“Mastercard is committed to bringing people closer to what they love and supporting Priceless causes,” said Rustom Dastoor, EVP of Marketing and Communications for the Americas, Mastercard. “Our partnership with the Jonas Brothers is more than just creating a unifying anthem to raise awareness for a cause; it’s about inspiring cardholders to join us in supporting Stand Up To Cancer. When we come together, we know that we can make a difference.”  

The fans’ heartwarming reactions and inspiring journeys are captured in a new music video, which marks the official debut of the song and serves as the anthem for Mastercard’s campaign.  A special airing of the video will debut during tonight’s 2025 MLB All-Star Game Presented by Mastercard on FOX following SU2C’s Placard Moment™. Immediately after, the full music video will be available on Mastercard’s YouTube and Instagram. Fans and supporters are encouraged to tune in to Mastercard’s social channels (@Mastercard) to watch and share how they #StandUpWithMastercard, showing the world how everyone, everywhere, can help make a difference.

“Cancer has impacted so many people all over the world. Teaming up with Mastercard to uplift fans who’ve found hope and healing in our music means so much to us,” said the Jonas Brothers. “‘I Can’t Lose’ is a song we hope can carry different meanings for everyone who hears it and, for those who need it, a reminder of their own strength.”

Through a 15-year collaboration, Mastercard has donated more than $75 million to Stand Up To Cancer in support of their mission to eliminate the disease. To learn more about the campaign and how to get involved, please visit mastercard.com/SU2C. 

“At Stand Up To Cancer, we believe in the power of community, storytelling, and shared purpose,” said Rusty Robertson, SU2C co-founder. “This collaboration with Mastercard and the Jonas Brothers captures all of that—it celebrates the resilience of those impacted by cancer and gives people an easy, meaningful way to take action. We’re honored to be part of a campaign that turns everyday moments into life-changing support for cancer research.”